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Compound CK

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Product Overview
Product Name Compound CK
CAS39262-14-1
FormulaC36H62O8
MW622.87
Appearance 白色粉末
Melting point181-183 °C
Boiling point723.1±60.0 °C | Condition: Press: 760 Torr
PKa12.94±0.70 | Condition: Most Acidic Temp: 25 °C
Product details

WKQ-0000459

中文名稱:人參皂苷CK

中文別名:20(S)-人參皂苷CK;人參皂苷C-K;人參皂苷K;20(S)-人參皂苷C-K;(2S,3R,4S,5S,6R)-2-(((S)-2-((3S,5R,8R,9R,10R,12R,13R,14R,17S)-3,12-二羥基-4,4,8,10,14-五甲基十六氫-1H-環(huán)戊二稀并[a]菲-17-基)-6-甲基庚-5-烯-2-基)氧基)-6-(羥甲基)四氫-2H-吡喃-3,4,5-三醇

英文名稱:Compound CK

英文別名:(3β,12β)-3,12-Dihydroxydammar-24-en-20-yl β-D-glucopyranoside;20(S)-Protopanaxadiol 20-O-D-glucopyranoside;20(S)-Protopanaxadiol 20-O-β-D-glucopyranoside;20-O-β-D-Glucopyranosyl-20(S)-protopanaxadiol;20-O-β-Glucopyranosyl-20(S)-protopanaxadiol;20S-Protopanaxadiol 20-O-β-D-glucopyranoside;3-O-Deglucosylginsenoside F2;Compound k;Ginsenoside C-K;Ginsenoside IH901;Ginsenoside K;Ginsenoside M1;Ginsenoside compound K;Ginsenoside metabolite M1;IH 901;LCHK 168;NT3 VAN SC6;Protopanaxadiol 20-O-glucoside;

分子式:C36H62O8

分子量:622.87

CAS號(hào):39262-14-1

純度:HPLC≥98%

熔點(diǎn):181-183 °C

沸點(diǎn):723.1±60.0 °C | Condition: Press: 760 Torr

密度:1.19±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr

酸系度數(shù):12.94±0.70 | Condition: Most Acidic Temp: 25 °C

儲(chǔ)存條件:-20℃,干燥、避光、密封

規(guī)格:5mg10mg20mg50mg100mg500mg1g2g等應(yīng)客戶需求包裝

供應(yīng)單位:四川省維克奇生物科技有限公司

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Related literature
Ginsenoside compound K exerts antitumour effects in renal cell carcinoma via regulation of ROS and lncRNA THOR
Source:SCI:ONCOLOGY REPORTS Author:Shuqiu Chen Notes:影響因子:3.906
Reference description

All cells were cultured in RPMI-1640 medium (Gibco; Thermo Fisher Scientific, Inc.) with 10% heat-inactivated foetal bovine serum (FBS; HyClone; Cytiva), 100 U/ml penicillin and 100 μg/ml streptomycin (Sigma-Aldrich; Merck KGaA) at 37°C in a humidified 5% CO2 atmosphere. CK was purchased from Sichuan WeiKeqi Biological Technology Co., Ltd. Pan-caspase inhibitor z-VAD was obtained from Sigma-Aldrich (Merck KGaA) and was used at a concentration of 10 μM at 37°C.

Antidepressant-like effects of ginsenosides: A comparison of ginsenoside Rb3 and its four deglycosylated derivatives, Rg3, Rh2, compound K, and 20(S)-protopanaxadiol in mice models of despair
Source:SCI:PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR Author:Hualin Zhang Notes:影響因子:2.781
Reference description

The ginsenoside Rb3 (Rb3) was isolated from SCLPN, and its structure was characterized by spectroscopic analysis with both ESI-MS and 13C NMR. 20(S)-Ginsenoside Rg3 (Rg3, Lot No.: 14,197–60-5-15-1), 20(S)-ginsenoside Rh2 (Rh2, Lot No.: 78214-33-2-14-6), compound K (C-K, Lot No.: 39262-14-1-14-9) and 20(S)-protopanaxadiol (PPD, Lot No.: 30636-90-9-14-2) were supplied by Sichuan Weikeqi Biological Technology Co. Ltd. (Chengdu, China). These compounds are white powders with a purity of 98%, which was verified by high

Effects of compound K, a metabolite of ginsenosides, on memory and cognitive dysfunction in db/db mice involve the inhibition of ER stress and the NLRP3 inflammasome pathway
Source:SCI:Food & Function Author:Chu-Wen Li Notes:影響因子:4.171
Reference description

Ginsenoside compound K (CK, purity: UV ≥ 98%) was obtained from Weikeqi

Biological Technology (Sichuan, China), while sodium carboxymethylcellulose (CMCNa), glucose and insulin solutions were acquired from Sigma-Aldrich (MO, USA)


Effects of ginsenoside compound K combined with cisplatin on the proliferation, apoptosis and epithelial mesenchymal transition in MCF-7 cells of human breast cancer
Source:SCI:PHARMACEUTICAL BIOLOGY Author:Keqiang Zhang Notes:影響因子:1.241
Reference description

CK (purity?>?98%) was provided by Weikeqi Biological Technology Co. (Shichuan, China). DDP was purchased from Haosen Pharmaceutical Co., Ltd. (Jiangsu, China).

Structure–inhibition relationship of ginsenosides towards UDP-glucuronosyltransferases (UGTs)
Source:SCI:TOXICOLOGY AND APPLIED PHARMACOLOGY Author:Zhong-Ze Fang Notes:影響因子:3.975
Reference description

Recombinant human UGT isoforms (UGT1A1, UGT1A6, UGT1A7, UGT1A8, UGT1A9, UGT1A10, UGT2B7, UGT2B15) expressed in baculovirus-infected insect cells were obtained from BD Gentest Corp. (Woburn, MA, USA). Ginsenosides Rb1, Rb2, Rc, Rd, Rg3, Rh2, C-K, ppd, ppt, Re, Rg1, Rh1, F1, and F2 were purchased from Sichuan Weikeqi Biotechnology Company (Chengdu, Sichuan, China). The purity of these compounds was above 95%. All other reagents were of HPLC grade or of the highest grade commercially available.

Effect of steam-processing of the Panax ginseng root on its inducible activity on granulocyte-colony stimulating factor secretion in intestinal epithelial cells in vitro
Source:SCI:JOURNAL OF ETHNOPHARMACOLOGY Author:Kewen Ding Notes:影響因子:4.36
Reference description

Isomaltose was purchased from Tokyo Chemical Industry (Tokyo, Japan). Protopanaxatriol and protopanaxadiol were obtained from ChromaDex (Irvine, CA). Compound K, ginsenosides Rh1, Rd, F1, F2, Rg3, and Rh2 were obtained from Sichuan Weikeqi Biological Technology (Chengdu, Sichuam, China). Lectin from Phytolacca americana (pokeweed mitogen, PWM), dextran standards certified according to Deutsches Institut für Normung (molecular weight; 668 kDa), Dulbecco’s modified Eagle’s medium

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